Research Projects: Oncology
- Dissecting inflammation and metabolism interplay at glioblastoma/blood-brain barrier interface to develop new therapies
- Effects of non-coding RNA on mitochondrial metabolism in non-small cell lung cancer
- Inducing ferroptosis by remodelling the intracellular lipid pools: a new weapon to kill chemoresistant cells
- Interconnections among tyrosine kinase receptors, glutamine metabolism, and stress response in breast cancer
- Metabolic analysis of NSCLC to improve patient stratification and identify new biomarkers of cancer progression and metastasis
- Obesity as determinant of response to drug therapy: unveiling new predicting biomarkers, moving to new therapeutic strategies
- Role of membrane trafficking proteins in the metabolic plasticity of breast cancer
- Targeting metabolic vulnerabilities to overcome resistance to therapies in solid tumors
- The metabolic and antioxidant strategies targeting the inflammatory triad of TGFβ, TNFα and vitamin D to fight cancer progression
- The multidimensional landscape of residual colorectal tumours after chemotherapy
Projects already developed using the metabolomics analysis service
- Sabrina Arena
Identification of metabolic vulnerabilities in prostate cancer - Tiziana Crepaldi
Interconnections among tyrosine kinase receptors, glutamine metabolism, and stress response in breast cancer - Gabriella Doronzo - Alessandra Merlini
Studio delle caratteristiche immuno-metaboliche del microambiente e del parenchima tumorale in pazienti affetti da sarcoma epitelioide tramite tecniche di metabolomica spaziale e imaging-mass cytometry per l’individuazione di meccanismi di resistenza alle terapie convenzionali e nuovi potenziali target terapeutici